ceesdekker.net for Dummies

ceesdekker.net for Dummies

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‘The next is nanopores, which happens to be our oldest line of investigate and that has now brought about DNA sequencers dependant on nanopores. We pull unique DNA strands via a nanopore and will then examine from the nucleotide sequence. Really just lately, we even managed to examine out an individual protein for The very first time utilizing this technique. But this line of research is don't just about producing equipment, but in addition about genuine Organic issues.

You frequently get involved in conversations about science and faith. You have got also prepared a number of textbooks on the subject. Don’t you are convinced at some time we will know anything and that God’s job is going to be more than?

Multicolor imaging in the bacterial nucleoid and cell division proteins with blue, orange, and in the vicinity of-infrared fluorescent proteins

Our work was rapidly followed up by Other individuals, most notably by Phaedon Avouris and colleagues at IBM, who in October 1998 revealed their results on transistors constructed from one- and multi-walled carbon nanotubes in Used Physics Letters.

This yielded a breakthrough. In just just a few months, we were in the position to measure transportation via somebody single-walled carbon nanotube. Dependant on minimal-temperature experiments by a superb PhD college student in my team, Sander Tans (now a valued colleague and professor at Delft University of Technology using an Lively analysis lab at AMOLF in Amsterdam), we confirmed that carbon nanotubes had been authentic quantum wires with very prolonged (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic behaviour.

Microbiology has only existed for the century, due to the fact we began to analyze micro-organisms more seriously. I thought nanobiology was an suitable phrase, since all ceesdekker.net molecular biological pertinent interactions happen on the nanoscale: a protein is a number of nanometres in sizing, DNA is two nm thick.’

‘At first we looked at biological units having a Bodily perspective and acted on The premise of the resources we understood. It took a number of years prior to we started out Performing more on the big biological concerns. I then began to call it nanobiology, a term that did not exist at time.

Finding out DNA loop extrusion by SMC proteins for chromosome architecture with single-molecule assays.

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It was throughout this period that Dekker completed investigation on magnetic spin devices and on noise in superconductors and semiconductors.

An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes

Later on we spoke yet again briefly because Dekker felt that our discussion of his faith speedily turned purely philosophical, Whilst Additionally, it concretely aids him in his get the job done.

Visualization of unstained DNA nanostructures with advanced in-target transmission electron microscopy tactics

Sound-condition nanopores have demonstrated to generally be a shockingly versatile probe for one-molecule analysis of DNA. I'll explain several of our new results – exclusively DNA knots – together with our initiatives to grow the capabilities of sound-state nanopores even additional, within the direction of one-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.